This Simpsons Vine is the video of the 2010's youtube.com

Reasons:

1. It's a Vine, reminding us that anything we like on the internet can be taken away from us. We loved social media and now it has become an occasionally leaky roof, so hum drum we don't feel gratitude for it when it works, when it fails us we escape under another leaky roof. It stores our memories yet can make them disappear like a photobook in a fire. I don't want to go back to earlier cultural forms, but a large proportion of the promise never materialized. Of the rest, majority is convenience and then comes the weird and occasionally wonderful.
2. we didn't have a future in 2010's as vaporwave on the background suggests.
3. The Simpsons is finally old enough to be an object of nostalgia. No gestures toward the sorry state it has evolved since is made. Neither have adult animated sitcoms still escaped its influence to a great success. That is too, very 2010's.
4. This is a degraded copy of the original because the more bandwidth we get, the less we can get the online giants not to compress our data in unforeseen ways.
5. The fantasy of escaping surveillance, going off the grid, being unnoticed strike to me as more significant in this Vine than the fantasy of children going on a road trip.
6. Anyone can do multimedia that catches on and isn't just a funny meme, footage of an odd event or a made up tale ostensibly told as true. People seriously consider this aspirational and it's just a few seconds long loop, cinematograph with music.